Impaired Mitochondrial Biogenesis Contributes to Mitochondrial Dysfunction in Alzheimer's Disease

Mitochondrial dysfunction is a prominent feature of Alzheimer's disease (AD) brain. Our prior studies demonstrated reduced mitochondrial number in susceptible hippocampal neurons in the brain from AD patients and in M17 cells overexpressing FAD-causing APP mutant (APPswe). In the current study,...

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Detaylı Bibliyografya
Asıl Yazarlar: Sheng, Baiyang, Wang, Xinglong, Su, Bo, Lee, Hyoung-gon, Casadesus, Gemma, Perry, George, Zhu, Xiongwei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253532/
https://ncbi.nlm.nih.gov/pubmed/22077634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07581.x
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