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Muscarinic receptor/G-protein coupling is reduced in the dorsomedial striatum of cognitively impaired aged rats
Behavioral flexibility, the ability to modify responses due to changing task demands, is detrimentally affected by aging with a shift towards increased cognitive rigidity. The neurobiological basis of this cognitive deficit is not clear although striatal cholinergic neurotransmission has been implic...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253526/ https://ncbi.nlm.nih.gov/pubmed/22085876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2011.10.048 |
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