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In vivo and transcriptome-wide identification of RNA binding protein target sites
Animal mRNAs are regulated by hundreds of RNA binding proteins (RBPs). The identification of RBP targets is crucial for understanding their function. A recent method, PAR-CLIP, uses photoreactive nucleosides to crosslink RBPs to target RNAs in cells prior to immunoprecipitation. Here, we establish i...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253457/ https://ncbi.nlm.nih.gov/pubmed/22152485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.009 |
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