In vivo and transcriptome-wide identification of RNA binding protein target sites

Animal mRNAs are regulated by hundreds of RNA binding proteins (RBPs). The identification of RBP targets is crucial for understanding their function. A recent method, PAR-CLIP, uses photoreactive nucleosides to crosslink RBPs to target RNAs in cells prior to immunoprecipitation. Here, we establish i...

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Hlavní autoři: Jungkamp, AC, Stoeckius, M, Mecenas, D, Grün, D, Mastrobuoni, G, Kempa, S, Rajewsky, N
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253457/
https://ncbi.nlm.nih.gov/pubmed/22152485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.009
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