Increased cavernosal relaxation by Phoneutria nigriventer toxin, PnTx2-6, via activation at NO/cGMP signaling

Erectile dysfunction mechanisms in diabetic patients are multifactorial and often lead to resistance to current therapy. Animal toxins have been used as pharmacological tools to study penile erection. Human accidents involving the venom of Phoneutria nigriventer spider are characterized by priapism....

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Autores principales: Nunes, K.P., Wynne, B.M., Cordeiro, M.N., Borges, M.H., Richardson, M, Leite, R., DeLima, M.E., Webb, R. C
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253321/
https://ncbi.nlm.nih.gov/pubmed/21975567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijir.2011.47
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