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Overexpression of ADK in human astrocytic tumors and peritumoral tissue is related to tumor-associated epilepsy
PURPOSE: Adenosine kinase (ADK), a largely astrocyte-based metabolic enzyme, regulates adenosine homeostasis in the brain. Overexpression of ADK decreases extracellular adenosine and consequently leads to seizures. We hypothesized that dysfunction in the metabolism of tumor astrocytes is related to...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3253237/ https://ncbi.nlm.nih.gov/pubmed/22092111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2011.03306.x |
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