Clozapine Functions Through the Prefrontal Cortex Serotonin 1A Receptor to Heighten Neuronal Activity via Calmodulin Kinase II-NMDA Receptor Interactions

Aberrant dopamine release in the prefrontal cortex (PFC) is believed to underlie schizophrenia, but the mechanistic pathway through which a widely used antipsychotic, clozapine (Clz), evokes neurotransmitter-releasing electrical stimulation is unclear. We analyzed Clz-evoked regulation of neuronal a...

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Main Authors: Purkayastha, Sudarshana, Ford, Jason, Kanjilal, Baishali, Diallo, Souleymane, Del Rosario Inigo, Joseph, Neuwirth, Lorenz, El Idrissi, Abdelsem, Ahmed, Zaghloul, Wieraszko, Andrzej, Efrain, C., Azmitia, Banerjee, Probal
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253201/
https://ncbi.nlm.nih.gov/pubmed/22044428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07565.x
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