Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation

BACKGROUND: Obesity is characterized by inflammation, caused by increase in proinflammatory cytokines, a key factor for the development of insulin resistance. SR141716A, a cannabinoid receptor 1 (CB1) antagonist, shows significant improvement in clinical status of obese/diabetic patients. Therefore,...

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Bibliographic Details
Main Authors: Murumalla, Ravi, Bencharif, Karima, Gence, Lydie, Bhattacharya, Amritendu, Tallet, Frank, Gonthier, Marie-Paule, Petrosino, Stefania, di Marzo, Vincenzo, Cesari, Maya, Hoareau, Laurence, Roche, Régis
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253048/
https://ncbi.nlm.nih.gov/pubmed/22087859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-8-33
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