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HCN channelopathies: pathophysiology in genetic epilepsy and therapeutic implications
Hyperpolarization-activated cyclic nucleotide-gated channels (HCN) can act as pacemakers in the brain making them strong candidates for driving aberrant hypersynchronous network activity seen in epilepsy. Transcriptional changes in HCN channels occur in several animal models of epilepsy. However, on...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252965/ https://ncbi.nlm.nih.gov/pubmed/21615728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01507.x |
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