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Characterization and adaptive optical correction of aberrations during in vivo imaging in the mouse cortex

The signal and resolution during in vivo imaging of the mouse brain is limited by sample-induced optical aberrations. We find that, although the optical aberrations can vary across the sample and increase in magnitude with depth, they remain stable for hours. As a result, two-photon adaptive optics...

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Detalhes bibliográficos
Main Authors: Ji, Na, Sato, Takashi R., Betzig, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252919/
https://ncbi.nlm.nih.gov/pubmed/22190489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109202108
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