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The rational design of a synthetic polymer nanoparticle that neutralizes a toxic peptide in vivo

Synthetic polymer nanoparticles (NPs) that bind venomous molecules and neutralize their function in vivo are of significant interest as “plastic antidotes.” Recently, procedures to synthesize polymer NPs with affinity for target peptides have been reported. However, the performance of synthetic mate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoshino, Yu, Koide, Hiroyuki, Furuya, Keiichi, Haberaecker, Walter W., Lee, Shih-Hui, Kodama, Takashi, Kanazawa, Hiroaki, Oku, Naoto, Shea, Kenneth J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252894/
https://ncbi.nlm.nih.gov/pubmed/22198772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112828109
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