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Ablation of Dido3 compromises lineage commitment of stem cells in vitro and during early embryonic development

The death inducer obliterator (Dido) locus encodes three protein isoforms, of which Dido3 is the largest and most broadly expressed. Dido3 is a nuclear protein that forms part of the spindle assembly checkpoint (SAC) and is necessary for correct chromosome segregation in somatic and germ cells. Here...

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Detalhes bibliográficos
Main Authors: Fütterer, A, Raya, Á, Llorente, M, Izpisúa-Belmonte, J C, de la Pompa, J L, Klatt, P, Martínez-A, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252825/
https://ncbi.nlm.nih.gov/pubmed/21660050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.62
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