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From Agonist to Antagonist: Structure and Dynamics of Innate Immune Glycoprotein MD-2 upon Recognition of Variably Acylated Bacterial Endotoxins
The human immune response to an infection by Gram-negative bacteria involves detection of lipopolysaccharides (LPS), also known as endotoxins, which comprise the bacterial outer cell wall. Distinct from mammalian glycolipid structures, LPS have a conserved chemical pattern that is recognized by the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252744/ https://ncbi.nlm.nih.gov/pubmed/21924775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.08.003 |
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