Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, 3673 screened controls and >1 M imputed single-nucleotide polymorphisms (SNPs)). No SNPs achieved genome-wide significance...

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Main Authors: Wray, N R, Pergadia, M L, Blackwood, D H R, Penninx, B W J H, Gordon, S D, Nyholt, D R, Ripke, S, MacIntyre, D J, McGhee, K A, Maclean, A W, Smit, J H, Hottenga, J J, Willemsen, G, Middeldorp, C M, de Geus, E J C, Lewis, C M, McGuffin, P, Hickie, I B, van den Oord, E J C G, Liu, J Z, Macgregor, S, McEvoy, B P, Byrne, E M, Medland, S E, Statham, D J, Henders, A K, Heath, A C, Montgomery, G W, Martin, N G, Boomsma, D I, Madden, P A F, Sullivan, P F
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252611/
https://ncbi.nlm.nih.gov/pubmed/21042317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2010.109
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