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The cost of large numbers of hypothesis tests on power, effect size and sample size

Advances in high-throughput biology and computer science are driving an exponential increase in the number of hypothesis tests in genomics and other scientific disciplines. Studies using current genotyping platforms frequently include a million or more tests. In addition to the monetary cost, this i...

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Detalhes bibliográficos
Main Authors: Lazzeroni, L C, Ray, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252610/
https://ncbi.nlm.nih.gov/pubmed/21060308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2010.117
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