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Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast

The evolutionarily conserved Mediator complex is required for transcription of nearly all RNA Pol II-dependent promoters, with the tail module serving to recruit Mediator to active promoters in current models. However, transcriptional dependence on tail module subunits varies in a gene-specific mann...

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Detalhes bibliográficos
Main Authors: Ansari, Suraiya A, Ganapathi, Mythily, Benschop, Joris J, Holstege, Frank C P, Wade, Joseph T, Morse, Randall H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252575/
https://ncbi.nlm.nih.gov/pubmed/21971086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.362
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