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Development of Responder Definitions for Fibromyalgia Clinical Trials

OBJECTIVE: To develop responder definitions for fibromyalgia clinical trials using key symptom and functional domains. METHODS: 24 candidate responder definitions were developed by expert consensus and evaluated in 12 randomized, placebo-controlled fibromyalgia trials of 4 medications. For each defi...

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Detalhes bibliográficos
Main Authors: Arnold, Lesley M., Williams, David A., Hudson, James I., Martin, Susan A., Clauw, Daniel J., Crofford, Leslie J., Wang, Fujun, Emir, Birol, Lai, Chinglin, Zablocki, Rong, Mease, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252491/
https://ncbi.nlm.nih.gov/pubmed/21953205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33360
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