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Chemotherapy-induced cognitive impairment is associated with decreases in cell proliferation and histone modifications

BACKGROUND: In this study, we examined the effects of cyclophosphamide, methothrexate, and 5-Fluorouracil (CMF) drug combination on various aspects of learning and memory. We also examined the effects of CMF on cell proliferation and chromatin remodeling as possible underlying mechanisms to explain...

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Hlavní autoři: Briones, Teresita L, Woods, Julie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252305/
https://ncbi.nlm.nih.gov/pubmed/22152030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-124
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