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Evaporative Light Scattering Detection Based HPLC Method for the Determination of Polysorbate 80 in Therapeutic Protein Formulations

An evaporative light scattering detection (ELSD) based high-performance liquid chromatography (HPLC) method is developed for the determination of polysorbate 80 (tween 80) in therapeutic protein formulations. The method is simple and overcomes the difficulties associated with specificity and sensiti...

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Detalhes bibliográficos
Main Authors: Nayak, Vikram S., Tan, Zhijun, Ihnat, Peter M., Russell, Reb J., Grace, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3252124/
https://ncbi.nlm.nih.gov/pubmed/22291052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chromsci/bmr015
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