Impact of anti-HER2 therapy on overall survival in HER2-overexpressing breast cancer patients with brain metastases

BACKGROUND: Trastuzumab-based therapy after diagnosis of brain metastases (BM) may improve survival due to prolonged systemic disease control. We investigated whether lapatinib may yield additional survival benefit. METHODS: Eighty patients with BM from HER2-positive breast cancer were identified. K...

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Detalhes bibliográficos
Main Authors: Bartsch, R, Berghoff, A, Pluschnig, U, Bago-Horvath, Z, Dubsky, P, Rottenfusser, A, DeVries, C, Rudas, M, Fitzal, F, Dieckmann, K, Mader, R M, Gnant, M, Zielinski, C C, Steger, G G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Clinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251869/
https://ncbi.nlm.nih.gov/pubmed/22127284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.531
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