Specific activity of cyclin-dependent kinase I is a new potential predictor of tumour recurrence in stage II colon cancer

BACKGROUND: There are no established biomarkers to identify tumour recurrence in stage II colon cancer. As shown previously, the enzymatic activity of the cyclin-dependent kinases 1 and 2 (CDK1 and CDK2) predicts outcome in breast cancer. Therefore, we investigated whether CDK activity identifies tu...

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Detalhes bibliográficos
Main Authors: Zeestraten, E C M, Maak, M, Shibayama, M, Schuster, T, Nitsche, U, Matsushima, T, Nakayama, S, Gohda, K, Friess, H, van de Velde, C J H, Ishihara, H, Rosenberg, R, Kuppen, P J K, Janssen, K-P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251853/
https://ncbi.nlm.nih.gov/pubmed/22108518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.504
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