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Design considerations for using PET as a response measure in single- and multi-center clinical trials
RATIONALE AND OBJECTIVES: PET is used to evaluate response to therapy with increasing interest in having PET provide endpoints for clinical trials. Here we demonstrate impacts of PET measurement error and choice of quantification method on clinical trial design. MATERIALS AND METHODS: Sample size wa...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251737/ https://ncbi.nlm.nih.gov/pubmed/22104290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.acra.2011.10.008 |
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