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Alcohol increases the permeability of airway epithelial tight junctions in Beas-2B and NHBE cells

BACKGROUND: Tight junctions form a continuous belt-like structure between cells and act to regulate paracellular signaling. Protein kinase C (PKC) has been shown to regulate tight junction assembly and disassembly and is activated by alcohol. Previous research has shown that alcohol increases the pe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Simet, Samantha. M., Wyatt, Todd A., DeVasure, Jane, Yanov, Daniel, Sisson, Joseph H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251733/
https://ncbi.nlm.nih.gov/pubmed/21950588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2011.01640.x
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