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Poke Weed Mitogen Requires Toll-Like Receptor Ligands for Proliferative Activity in Human and Murine B Lymphocytes

Poke weed mitogen (PWM), a lectin purified from Phytolacca americana is frequently used as a B cell-specific stimulus to trigger proliferation and immunoglobulin secretion. In the present study we investigated the mechanisms underlying the B cell stimulatory capacity of PWM. Strikingly, we observed...

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Detalhes bibliográficos
Main Authors: Bekeredjian-Ding, Isabelle, Foermer, Sandra, Kirschning, Carsten J., Parcina, Marijo, Heeg, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251602/
https://ncbi.nlm.nih.gov/pubmed/22238657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029806
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