Cardiac-Oxidized Antigens Are Targets of Immune Recognition by Antibodies and Potential Molecular Determinants in Chagas Disease Pathogenesis

Trypanosoma cruzi elicits reactive oxygen species (ROS) of inflammatory and mitochondrial origin in infected hosts. In this study, we examined ROS-induced oxidative modifications in the heart and determined whether the resultant oxidized cardiac proteins are targets of immune response and of patholo...

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Detalhes bibliográficos
Main Authors: Dhiman, Monisha, Zago, Maria Paola, Nunez, Sonia, Amoroso, Alejandro, Rementeria, Hugo, Dousset, Pierre, Burgos, Federico Nunez, Garg, Nisha Jain
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251564/
https://ncbi.nlm.nih.gov/pubmed/22238578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028449
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