Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells

Throughout life, one's blood supply depends on sustained division of hematopoietic stem cells (HSCs) for self-renewal and differentiation. Within the bone marrow microenvironment, an adhesion-dependent or -independent niche system regulates HSC function. Here we show that a novel adhesion-depen...

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Autores principales: Umemoto, Terumasa, Yamato, Masayuki, Ishihara, Jun, Shiratsuchi, Yoshiko, Utsumi, Mika, Morita, Yohei, Tsukui, Hiroko, Terasawa, Masao, Shibata, Takehiko, Nishida, Kohji, Kobayashi, Yoshiro, Petrich, Brian G., Nakauchi, Hiromitsu, Eto, Koji, Okano, Teruo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2012
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251239/
https://ncbi.nlm.nih.gov/pubmed/22096247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-335430
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