Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A

We have generated 3 mouse lines, each with a different mutation in the nonmuscle myosin II-A gene, Myh9 (R702C, D1424N, and E1841K). Each line develops MYH9-related disease similar to that found in human patients. R702C mutant human cDNA fused with green fluorescent protein was introduced into the f...

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Detalhes bibliográficos
Main Authors: Zhang, Yingfan, Conti, Mary Anne, Malide, Daniela, Dong, Fan, Wang, Aibing, Shmist, Yelena A., Liu, Chengyu, Zerfas, Patricia, Daniels, Mathew P., Chan, Chi-Chao, Kozin, Elliot, Kachar, Bechara, Kelley, Michael J., Kopp, Jeffrey B., Adelstein, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251230/
https://ncbi.nlm.nih.gov/pubmed/21908426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-358853
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