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Screening for anticoagulant heparan sulfate octasaccharides and fine structure characterization using tandem mass spectrometry

Heparan sulfate (HS) is a sulfated glycosaminoglycan located on the surface and extracellular matrix of mammalian cells. HS is constituted of highly N-sulfated domains (NS domains) interrupted by lower sulfation domains. The arrangement of these domains dictates the function of HS which is mainly in...

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Bibliographische Detailangaben
Hauptverfasser: Naimy, Hicham, Leymarie, Nancy, Zaia, Joseph
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251171/
https://ncbi.nlm.nih.gov/pubmed/20345121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100135d
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