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Increased expression of histone demethylase JHDM1D under nutrient starvation suppresses tumor growth via down-regulating angiogenesis

Histone demethylase JHDM1D (also known as KDM7A) modifies the level of methylation in histone and participates in epigenetic gene regulation; however, the role of JHDM1D in tumor progression is unknown. Here, we show that JHDM1D plays a tumor-suppressive role by regulating angiogenesis. Expression o...

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Detalhes bibliográficos
Main Authors: Osawa, Tsuyoshi, Muramatsu, Masashi, Wang, Feng, Tsuchida, Rika, Kodama, Tatsuhiko, Minami, Takashi, Shibuya, Masabumi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251107/
https://ncbi.nlm.nih.gov/pubmed/22143793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108462109
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