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A small molecule differentiation inducer increases insulin production by pancreatic β cells

New drugs for preserving and restoring pancreatic β-cell function are critically needed for the worldwide epidemic of type 2 diabetes and the cure for type 1 diabetes. We previously identified a family of neurogenic 3,5-disubstituted isoxazoles (Isx) that increased expression of neurogenic different...

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Detalhes bibliográficos
Main Authors: Dioum, Elhadji M., Osborne, Jihan K., Goetsch, Sean, Russell, Jamie, Schneider, Jay W., Cobb, Melanie H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251102/
https://ncbi.nlm.nih.gov/pubmed/22143803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118526109
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