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Atrial-Selective Sodium Channel Block Strategy to Suppress Atrial Fibrillation: Ranolazine versus Propafenone

Ranolazine has been shown to produce atrial-selective depression of sodium channel-dependent parameters and suppress atrial fibrillation (AF) in a variety of experimental models. The present study contrasts the effects of ranolazine and those of a clinically used anti-AF class IC agent, propafenone....

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Detalhes bibliográficos
Main Authors: Burashnikov, Alexander, Belardinelli, Luiz, Antzelevitch, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251016/
https://ncbi.nlm.nih.gov/pubmed/22005044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.186395
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