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Stability and Multiattractor Dynamics of a Toggle Switch Based on a Two-Stage Model of Stochastic Gene Expression

A toggle switch consists of two genes that mutually repress each other. This regulatory motif is active during cell differentiation and is thought to act as a memory device, being able to choose and maintain cell fate decisions. Commonly, this switch has been modeled in a deterministic framework whe...

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מידע ביבליוגרפי
Main Authors: Strasser, Michael, Theis, Fabian J., Marr, Carsten
פורמט: Artigo
שפה:Inglês
יצא לאור: The Biophysical Society 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250690/
https://ncbi.nlm.nih.gov/pubmed/22225794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.11.4000
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