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Role of Channel Lysines and the “Push Through a One-Way Valve” Mechanism of the Viral DNA Packaging Motor
Linear double-stranded DNA (dsDNA) viruses package their genomes into preformed protein shells via nanomotors using ATP as an energy source. The central hub of the bacteriophage ϕ29 DNA-packaging motor contains a 3.6-nm channel for dsDNA to enter during packaging and to exit during infection. The ne...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250684/ https://ncbi.nlm.nih.gov/pubmed/22225806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.11.4013 |
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