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miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes

Mitochondria are central to the execution of apoptosis, and the Bcl-2 protein family of pro- and anti-apoptotic proteins interacts with mitochondria to regulate apoptosis. Using bioinformatics we predicted that miR-181, a microRNA expressed in brain, could target the 3′UTRs of Bcl-2 family members B...

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Bibliografische gegevens
Hoofdauteurs: Ouyang, Yi-Bing, Lu, Yu, Yue, Sibiao, Giffard, Rona G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250561/
https://ncbi.nlm.nih.gov/pubmed/21958558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2011.09.001
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