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miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes
Mitochondria are central to the execution of apoptosis, and the Bcl-2 protein family of pro- and anti-apoptotic proteins interacts with mitochondria to regulate apoptosis. Using bioinformatics we predicted that miR-181, a microRNA expressed in brain, could target the 3′UTRs of Bcl-2 family members B...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250561/ https://ncbi.nlm.nih.gov/pubmed/21958558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2011.09.001 |
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