Distinct Roles for Aryl Hydrocarbon Receptor Nuclear Translocator and Ah Receptor in Estrogen-Mediated Signaling in Human Cancer Cell Lines

The activated AHR/ARNT complex (AHRC) regulates the expression of target genes upon exposure to environmental contaminants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Importantly, evidence has shown that TCDD represses estrogen receptor (ER) target gene activation through the AHRC. Our data...

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Autores principales: Labrecque, Mark P., Takhar, Mandeep K., Hollingshead, Brett D., Prefontaine, Gratien G., Perdew, Gary H., Beischlag, Timothy V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250444/
https://ncbi.nlm.nih.gov/pubmed/22235307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029545
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