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A-Site Residues Move Independently from P-Site Residues in all-Atom Molecular Dynamics Simulations of the 70S Bacterial Ribosome

The ribosome is a large macromolecular machine, and correlated motion between residues is necessary for coordinating function across multiple protein and RNA chains. We ran two all-atom, explicit solvent molecular dynamics simulations of the bacterial ribosome and calculated correlated motion betwee...

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Bibliografiske detaljer
Main Authors: Brandman, Relly, Brandman, Yigal, Pande, Vijay S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250440/
https://ncbi.nlm.nih.gov/pubmed/22235290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029377
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