Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle

Although denervation has long been implicated in aging muscle, the degree to which it is causes the fiber atrophy seen in aging muscle is unknown. To address this question, we quantified motoneuron soma counts in the lumbar spinal cord using choline acetyl transferase immunhistochemistry and quantif...

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Bibliographic Details
Main Authors: Rowan, Sharon L., Rygiel, Karolina, Purves-Smith, Fennigje M., Solbak, Nathan M., Turnbull, Douglas M., Hepple, Russell T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250397/
https://ncbi.nlm.nih.gov/pubmed/22235261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0029082
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