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Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow

Under homeostatic conditions, a proportion of senescent CXCR4(hi) neutrophils home from the circulation back to the bone marrow, where they are phagocytosed by bone marrow macrophages. In this study, we have identified an unexpected role for the anti-inflammatory molecule annexin A1 (AnxA1) as a cri...

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Autors principals: Dalli, Jesmond, Jones, Carla P., Cavalcanti, Danielle M., Farsky, Sandra H., Perretti, Mauro, Rankin, Sara M.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250241/
https://ncbi.nlm.nih.gov/pubmed/21957127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-182089
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