AT(1) Receptors in the Collecting Duct Directly Modulate the Concentration of Urine

Mice lacking AT(1) angiotensin receptors have an impaired capacity to concentrate the urine, but the underlying mechanism is unknown. To determine whether direct actions of AT(1) receptors in epithelial cells of the collecting duct regulate water reabsorption, we used Cre-Loxp technology to specific...

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Main Authors: Stegbauer, Johannes, Gurley, Susan B., Sparks, Matthew A., Woznowski, Magdalena, Kohan, Donald E., Yan, Ming, Lehrich, Ruediger W., Coffman, Thomas M.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2011
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250205/
https://ncbi.nlm.nih.gov/pubmed/22052052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010101095
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