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Human embryonic stem cell-derived neurons adopt and regulate the activity of an established neural network

Whether hESC-derived neurons can fully integrate with and functionally regulate an existing neural network remains unknown. Here, we demonstrate that hESC-derived neurons receive unitary postsynaptic currents both in vitro and in vivo and adopt the rhythmic firing behavior of mouse cortical networks...

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Bibliografiska uppgifter
Huvudupphovsmän: Weick, Jason P., Liu, Yan, Zhang, Su-Chun
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250161/
https://ncbi.nlm.nih.gov/pubmed/22106298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108487108
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