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Quinelorane, a dopamine D3/D2 receptor agonist, reduces prepulse inhibition of startle and ventral pallidal GABA efflux: Time course studies

Startle is inhibited when the startling stimulus is preceded 30–300 ms by a weak prepulse. Prepulse inhibition (PPI), an operational measure of sensorimotor gating, is deficient in schizophrenia patients, and reduced in rats and humans by dopamine agonists. The neural basis for the PPI-disruptive ef...

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Autores principales: Qu, Ying, Swerdlow, Neal R., Weber, Martin, Stouffer, David, Parsons, Loren H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250091/
https://ncbi.nlm.nih.gov/pubmed/18579193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2008.05.012
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