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In Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative Metabolites
Triclocarban (3,4,4′-trichlorocarbanilide; TCC) is widely used as an antibacterial in bar soaps. During use of these soaps, a significant portion of TCC is absorbed by humans. For the elimination from the body, glucuronidation plays a key role in both biliary and renal clearance. To investigate this...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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The American Society for Pharmacology and Experimental Therapeutics
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3250046/ https://ncbi.nlm.nih.gov/pubmed/21953915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042283 |
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