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In Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative Metabolites

Triclocarban (3,4,4′-trichlorocarbanilide; TCC) is widely used as an antibacterial in bar soaps. During use of these soaps, a significant portion of TCC is absorbed by humans. For the elimination from the body, glucuronidation plays a key role in both biliary and renal clearance. To investigate this...

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Bibliografiske detaljer
Main Authors: Schebb, N. H., Franze, B., Maul, R., Ranganathan, A., Hammock, B. D.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250046/
https://ncbi.nlm.nih.gov/pubmed/21953915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.111.042283
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