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Identification of the protease inhibitor miraziridine A in the Red sea sponge Theonella swinhoei

BACKGROUND: Miraziridine A, a natural peptide isolated from a marine sponge, is a potent cathepsin B inhibitor with a second-order rate constant of 1.5 × 10(4) M(-1) s(-1). In the present study, miraziridine A was isolated from the Red Sea sponge Theonella swinhoei on the basis of chromatographic an...

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Detalhes bibliográficos
Main Authors: Tabares, Paula, Degel, Björn, Schaschke, Norbert, Hentschel, Ute, Schirmeister, Tanja
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250042/
https://ncbi.nlm.nih.gov/pubmed/22224064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0974-8490.91047
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