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Formulation and Optimization of Mucoadhesive Nanodrug Delivery System of Acyclovir
Acyclovir is an antiviral drug used for the treatment of herpes simplex virus infections, with an oral bioavailability of only 10–20% [limiting absorption in gastrointestinal tract to duodenum and jejunum] and half-life of about 3 h, and is soluble only at acidic pH (pKa 2.27). Mucoadhesive polymeri...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Medknow Publications & Media Pvt Ltd
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249739/ https://ncbi.nlm.nih.gov/pubmed/22224033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0975-1483.90236 |
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