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Cannabinoid Receptor Type 1 (CB1) Activation Inhibits Small GTPase RhoA Activity and Regulates Motility of Prostate Carcinoma Cells

The cannabinoid receptor type 1 (CB1) is a G protein-coupled receptor that is activated in an autocrine fashion by the endocannabinoids (EC), N-arachidonoylethanolamine (AEA) and 2-arachidonoylglycerol (2-AG). The CB1 and its endogenous and synthetic agonists are emerging as therapeutic targets in s...

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Detalhes bibliográficos
Main Authors: Nithipatikom, Kasem, Gomez-Granados, Ana Doris, Tang, Alan T., Pfeiffer, Adam W., Williams, Carol L., Campbell, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249681/
https://ncbi.nlm.nih.gov/pubmed/22087025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1144
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