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Neonatal Exposure to Estradiol/Bisphenol A Alters Promoter Methylation and Expression of Nsbp1 and Hpcal1 Genes and Transcriptional Programs of Dnmt3a/b and Mbd2/4 in the RatProstate Gland Throughout Life

Evidence supporting an early origin of prostate cancer is growing. We demonstrated previously that brief exposure of neonatal rats to estradiol or bisphenol A elevated their risk of developing precancerous lesions in the prostate upon androgen-supported treatment with estradiol as adults. Epigenetic...

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Detalles Bibliográficos
Main Authors: Tang, Wan-yee, Morey, Lisa M., Cheung, Yuk Yin, Birch, Lynn, Prins, Gail S., Ho, Shuk-mei
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249669/
https://ncbi.nlm.nih.gov/pubmed/22109888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1308
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