Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo

The E2F-1 transcription factor is post-translationally modified and stabilized in response to various forms of DNA damage to regulate the expression of cell-cycle and pro-apoptotic genes. The sustained overexpression of E2F-1 is a characteristic feature of gastric cancer. In this study, we investiga...

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Bibliographic Details
Main Authors: Wang, Xiao-Tong, Xie, Yu-Bo, Xiao, Qiang
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2011
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249590/
https://ncbi.nlm.nih.gov/pubmed/21869593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2011.43.11.072
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