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Fuzzy oil drop model to interpret the structure of antifreeze proteins and their mutants

Mutations in proteins introduce structural changes and influence biological activity: the specific effects depend on the location of the mutation. The simple method proposed in the present paper is based on a two-step model of in silico protein folding. The structure of the first intermediate is ass...

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Hlavní autoři: Banach, Mateusz, Prymula, Katarzyna, Jurkowski, Wiktor, Konieczny, Leszek, Roterman, Irena
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249532/
https://ncbi.nlm.nih.gov/pubmed/21523554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-011-1033-4
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