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Angiopoietin-Like-2 and -3 Act Through Their Coiled-Coil Domains to Enhance Survival and Replating Capacity of Human Cord Blood Hematopoietic Progenitors

Several Angiopoietin-like (ANGPTL) molecules have been implicated in enhancement of ex-vivo expansion of murine and human (hu) hematopoietic stem cells, but there are no reports on hematopoietic progenitor cells (HPCs). We assessed purified recombinant endotoxin-free hu ANGPTL-2 Coiled-Coil (CC), -3...

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Detalhes bibliográficos
Main Authors: Broxmeyer, Hal E., Srour, Edward F., Cooper, Scott, Wallace, Carrie T., Hangoc, Giao, Youn, Byung-S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249507/
https://ncbi.nlm.nih.gov/pubmed/21983347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2011.09.004
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